プロフィール

2015年3月　東京大学理学部　化学科　卒業
2017年3月　東京大学大学院理学系研究科　化学専攻　修士課程　修了
2020年3月　東京大学大学院理学系研究科　化学専攻　博士課程　修了　(理学)
　　　　　 （2018年9月〜2018年11月:ドイツ・ボン大学 短期留学）
2020年4月　東京大学大学院工学系研究科　応用化学専攻 社会連携講座　特任助教

論文リスト

"Metal-dependent activity control of a compact-sized 8–17 DNAzyme based on metal-mediated unnatural base pairing"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Chem. Commun. 2024, 60, 288-291. [10.1039/D3CC05520E]

"Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases"
Y. Takezawa, K. Mori, W.-E. Huang, K. Nishiyama, T. Xing, T. Nakama, M. Shionoya
Nat. Commun. 2023, 14, 4759. [10.1038/s41467-023-40353-3]

"Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages"
T. Nakama, A. Rossen, R. Ebihara, M. Yagi-Utsumi, D. Fujita, K. kato, S. Sato, M. Fujita
Chem. Sci. 2023, 14, 2910–2914. [10.1039/d2sc05879k]

"Protein stabilization and refolding in a gigantic self-assembled cage"
D. Fujita, R. Suzuki, Y. Fujii, M. Yamada, T. Nakama, A. Matsugami, F. Hayashi, J.-K. Weng, M. Yagi-Utsumi, M. Fujita
Chem 2021, 7, 2672–2683. [10.1016/j.chempr.2021.08.005]

"Site-specific Polymerase Incorporation of Consecutive Ligand-containing Nucleotides for Multiple Metal-mediated Base Pairing"
T. Nakama, Y. Takezawa, M. Shionoya
Chem. Commun. 2021, 57, 1392–1395.[10.1039/d0cc07771b]

"Sharp Switching of DNAzyme Activity through the Formation of a Cu(II)‐Mediated Carboxyimidazole Base Pair"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Angew. Chem. Int. Ed. 2020, 59, 21488–21492. [10.1002/anie.202009579]

"Allosteric Regulation of DNAzyme Activities through Intrastrand Trans-formation Induced by Cu(II)-Mediated Artificial Base Pairing"
T. Nakama, Y. Takezawa, D. Sasaki, M. Shionoya
J. Am. Chem. Soc. 2020, 142, 10153–10162. [10.1021/jacs.0c03129]

"Enzymatic Synthesis of Cu(II)-responsive Deoxyribozymes through Polymerase Incorporation of Artificial Ligand-type Nucleotides"
Y. Takezawa, T. Nakama, M. Shionoya
J. Am. Chem. Soc. 2019, 141, 19342–19350. [10.1021/jacs.9b08955]

"Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions"
Y. Takezawa, S. Yoneda, J.-L. H. A. Duprey, T. Nakama, M. Shionoya
Chem. Sci. 2016, 7, 3006–3010. [10.1039/C6SC00383D]