Publications

2024

• Host‐in‐Host Complexation: Activating Classical Hosts through Complete Encapsulation within an M9L6 Coordination Cage
  K. Iizuka, H. Takezawa, M. Fujita
  Angew. Chem. Int. Ed. 2024, Accepted, e202422143. [ 10.1002/anie.202422143 ]
• Template and Solid-State Assisted Assembly of an M9L6 Expanded Coordination Cage for Medium-Sized-Molecule Encapsulation
  K. Iizuka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2024, 146, 32311–32316. [ 10.1021/jacs.4c14509 ]
• New workflow for the structure elucidation of trace amount natural products with microgram-scale crystalline sponge method: a scaled-down genome-mining study
  C. Park, T. Mitsuhashi, N. Wada, T. Kikuchi, M. Fujita
  Chem. Lett. 2024, 53, upae202. [ 10.1093/chemle/upae202 ]
• Physical Isolation of Single Protein Molecules within Well-Defined Coordination Cages to Enhance Their Stability
  R. Ebihara, T. Nakama, K. Morishima, M. Yagi-Utsumi, M. Sugiyama, D. Fujita, S. Sato, M. Fujita
  Angew. Chem. Int. Ed. 2024, , e202419476. [ 10.1002/anie.202419476 ]
• A Discrete Four-Stranded β-Sheet through Catenation of M2L2 Metal–Peptide Rings
  E. Tsunekawa, M. Fujita, T. Sawada
  Angew. Chem. Int. Ed. 2024, , e202416442. [ 10.1002/anie.202416442 ]
• Organic solvent-induced structural changes in a protein confined in a giant coordination cage
  H. Tamura, T. Nakama, A. Rossen, H. Ishikita, M. Fujita
  Chem. Lett. 2024, 53, upae101. [ 10.1093/chemle/upae101 ]
• Conformational Analysis of (+)-Germacrene D-4-ol Using the Crystalline Sponge Method to Elucidate the Origin of its Instability
  Y. Jung, T. Mitsuhashi, K. Kageyama, T. Kikuchi, S. Sato, M. Fujita
  Chem. Eur. J. 2024, 39, e202400512. [ 10.1002/chem.202400512 ]
• Functional Plasticity of a Viral Terpene Synthase, OILTS, that Shows Non–Specific Metal Cofactor Binding and Metal–dependent Biosynthesis
  Y. Jung, T. Mitsuhashi, T. Kikuchi, M. Fujita
  Chem. Eur. J. 2024, 30, e202304317. [ 10.1002/chem.202304317 ]
• Selective Synthesis and Functionalization of an Acyclic Methylene-Bridged-Arene Trimer in a Cage
  H. Takezawa, K. Iizuka, M. Fujita
  Angew. Chem. Int. Ed. 2024, 63, e202319140. [ 10.1002/anie.202319140 ]
• Rapid Analysis of Trace Amounts of Amino Acid Derivatives by a Formyl Group-Installed Crystalline Sponge
  B. Zhou, S. Utjapimuk, K. Yan, R. Dubey, T. Kikuchi, T. Mitsuhashi, M. Fujita
  Chem. Asian. J. 2024, 19, e202300969. [ 10.1002/asia.202300969 ]

2023

• Function and Structure of a Terpene Synthase Encoded in a Giant Virus Genome
  Y. Jung, T. Mitsuhashi, S. Sato, M. Senda, T. Senda, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 25966–25970. [ 10.1021/jacs.3c10603 ]
• Chemical Site-Differentiation of Calix[4]arenes through Enforced Conformations by Confinement in a Cage
  K. Iizuka, H. Takezawa, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 25971–25975. [ 10.1021/jacs.3c10720 ]
• Tetradehydro-Diels-Alder Reactions of Flexible Arylalkynes via Folding Inside a Molecular Cage
  G. R. Genov, H. Takezawa, H. Hayakawa, M. Fujita
  J. Am. Chem. Soc. 2023, 145, 17013–17017. [ 10.1021/jacs.3c06301 ]
• X-ray and Electron Diffraction Observations of Steric Zipper Interactions in Metal-Induced Peptide Cross-β Nanostructures
  E. Tsunekawa, Y. Otsubo, Y. Yamada, A. Ikeda, N. Adachi, M. Kawasaki, A. Takasu, S. Aramaki, T. Senda, S. Sato, S. Yoshida, M. Fujita, T. Sawada
  J. Am. Chem. Soc. 2023, 145, 16160–16165. [ 10.1021/jacs.3c04710 ]
• Synthetic Modulation of an Unstable Dehydrosecodine-type Intermediate and Its Encapsulation into a Confined Cavity Enable Its X-ray Crystallographic Observation
  G. Tay, T. Wayama, H. Takezawa, S. Yoshida, S. Sato, M. Fujita, H. Oguri
  Angew. Chem. Int. Ed. 2023, 62, e202305122. [ 10.1002/anie.202305122 ]
• Interconversion of Highly Entangled Polyhedra into Concave Polyhedra by Nitrate-Induced Ternary Coordination
  Y. Domoto, M. Abe, G. R. Genov, Z. Yu, M. Fujita
  Angew. Chem. Int. Ed. 2023, 62, e202303714. [ 10.1002/anie.202303714 ]
• Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages
  T. Nakama, A. Rossen, R. Ebihara, M. Yagi-Utsumi, D. Fujita, K. Kato, S. Sato, M. Fujita
  Chem. Sci. 2023, 14, 2910–2914. [ 10.1039/D2SC05879K ]

2022

• Self-Assembled Coordination Cage Enhances Reactivity of Confined Amides via Mechanical Bond-Twisting
  H. Tamura, H. Takezawa, M. Fujita, H. Ishikita
  Phys. Chem. Chem. Phys. 2022, 24, 21367–21371. [ 10.1039/D2CP03126D ]
• Selective Confinement of Rare-Earth-Metal Hydrates by a Capped Metallo-Cage under Aqueous Conditions
  R. Tabuchi, H. Takezawa, M. Fujita
  Angew. Chem. Int. Ed. 2022, 61, e202208866. [ 10.1002/anie.202208866 ]
• Self-assembly of nanostructures with high complexity based on metal⋯unsaturated-bond coordination
  Y. Domoto, M. Fujita
  Coord. Chem. Rev. 2022, 466, 214605. [ 10.1016/j.ccr.2022.214605 ]
• Electrophilic Spirocyclization of a 2-Biphenylacetylene via Conformational Fixing within a Hollow-Cage Host
  H. Takezawa, Y. Fujii, T. Murase, M. Fujita
  Angew. Chem. Int. Ed. 2022, 61, e202203970. [ 10.1002/anie.202203970 ]
• Amplification of weak chiral inductions for excellent control over the helical orientation of discrete topologically chiral (M₃L₂)_n polyhedra
  Y. Domoto, K. Yamamoto, S. Horie, Z. Yu, M. Fujita
  Chem. Sci. 2022, 13, 4372-4376. [ 10.1039/D2SC00111J ]
• Comprehensive Structural Analysis of the Bitter Components in Beer by the HPLC-assisted Crystalline Sponge Method
  Y. Taniguchi, T. Kikuchi, S. Sato, M. Fujita
  Chem. Eur. J. 2022, 28, e202103339. [ 10.1002/chem.202103339 ]
• Structure Analysis of Polyhalogenated Persistent Organic Pollutants by the Crystalline Sponge Method
  J. Chen, T. Kikuchi, K. Takagi, H. Kiyota, K. Adachi, T. Mitsuhashi, M. Fujita
  Chem. Lett. 2022, 51, 85-87. [ 10.1246/cl.210613 ]