Lab. Members
NAKAMA Takahiro
Research Assistant Professor |
Profile
2015.3 B.S. The University of Tokyo2017.3 M.S. The University of Tokyo
2018. 9-11 Visiting Student, M. Famulok lab., University of Bonn, Bonn, Germany
2020.3 Ph.D. of Science, The University of Tokyo
2020.4- Project Assistant Professor, The University of Tokyo
Publication list
"Physical Isolation of Single Protein Molecules within Well-Defined Coordination Cages to Enhance Their Stability"R. Ebihara, T. Nakama, K. Morishima, M. Yagi-Utsumi, M. Sugiyama, D. Fujita, S. Sato, M. Fujita
Angew. Chem. Int. Ed. 2024, Accepted, . [10.1002/anie.202419476]
"Organic solvent-induced structural changes in a protein confined in a giant coordination cage"
H. Tamura, T. Nakama, A. Rossen, H. Ishikita, M. Fujita
Chem. Lettt.. 2024, 53, upae101. [10.1093/chemle/upae101]
"Metal-dependent activity control of a compact-sized 8–17 DNAzyme based on metal-mediated unnatural base pairing"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Chem. Commun. 2024, 60, 288–291. [10.1039/D3CC05520E]
"Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases"
Y. Takezawa, K. Mori, W.-E. Huang, K. Nishiyama, T. Xing, T. Nakama, M. Shionoya
Nat. Commun. 2023, 14, 4759. [10.1038/s41467-023-40353-3]
"Hysteresis behavior in the unfolding/refolding processes of a protein trapped in metallo-cages"
T. Nakama, A. Rossen, R. Ebihara, M. Yagi-Utsumi, D. Fujita, K. kato, S. Sato, M. Fujita
Chem. Sci. 2023, 14, 2910–2914. [10.1039/d2sc05879k]
"Protein stabilization and refolding in a gigantic self-assembled cage"
D. Fujita, R. Suzuki, Y. Fujii, M. Yamada, T. Nakama, A. Matsugami, F. Hayashi, J.-K. Weng, M. Yagi-Utsumi, M. Fujita
Chem 2021, 7, 2672–2683. [10.1016/j.chempr.2021.08.005]
"Site-specific Polymerase Incorporation of Consecutive Ligand-containing Nucleotides for Multiple Metal-mediated Base Pairing"
T. Nakama, Y. Takezawa, M. Shionoya
Chem. Commun. 2021, 57, 1392–1395.[10.1039/d0cc07771b]
"Sharp Switching of DNAzyme Activity through the Formation of a Cu(II)‐Mediated Carboxyimidazole Base Pair"
Y. Takezawa, L. Hu, T. Nakama, M. Shionoya
Angew. Chem. Int. Ed. 2020, 59, 21488–21492. [10.1002/anie.202009579]
"Allosteric Regulation of DNAzyme Activities through Intrastrand Trans-formation Induced by Cu(II)-Mediated Artificial Base Pairing"
T. Nakama, Y. Takezawa, D. Sasaki, M. Shionoya
J. Am. Chem. Soc. 2020, 142, 10153–10162. [10.1021/jacs.0c03129]
"Enzymatic Synthesis of Cu(II)-responsive Deoxyribozymes through Polymerase Incorporation of Artificial Ligand-type Nucleotides"
Y. Takezawa, T. Nakama, M. Shionoya
J. Am. Chem. Soc. 2019, 141, 19342–19350. [10.1021/jacs.9b08955]
"Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions"
Y. Takezawa, S. Yoneda, J.-L. H. A. Duprey, T. Nakama, M. Shionoya
Chem. Sci. 2016, 7, 3006–3010. [10.1039/C6SC00383D]